About The Medical Condition Reperfusion Injury, Myocardial
Find the definition of the medical term Reperfusion Injury, Myocardial. Reperfusion Injury, Myocardial defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Reperfusion Injury, Myocardial
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What's The Definition Of The Medical Condition Reperfusion Injury, Myocardial?
Functional, metabolic, or structural changes in ischemic heart muscle thought to result from REPERFUSION to the ischemic areas. Changes can be fatal to muscle cells and may include edema with explosive cell swelling and disintegration, sarcolemma disruption, fragmentation of mitochondria, contraction band necrosis, enzyme washout, and calcium overload. Other damage may include hemorrhage and ventricular arrhythmias. One possible mechanism of damage is thought to be oxygen free radicals. Treatment currently includes the introduction of scavengers of oxygen free radicals, and injury is thought to be prevented by warm blood cardioplegic infusion prior to reperfusion.
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