About The Medical Condition Resistance-Associated Protein, Multidrug
Find the definition of the medical term Resistance-Associated Protein, Multidrug. Resistance-Associated Protein, Multidrug defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Resistance-Associated Protein, Multidrug
| Resistance-Associated Protein, Multidrug Medical Condition |
|---|
What's The Definition Of The Medical Condition Resistance-Associated Protein, Multidrug?
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the p-glycoprotein family of proteins.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Mange ‐ Infestations with arthropods of the subclass ACARI, superorder…
- Disease, Postphlebitic ‐ Post-thrombotic complications, including destruction of the valves…
- Emergency Treatment ‐ First aid or other immediate intervention for accidents or medical…
- Epidemic Acute Poliomyelitis ‐ An acute infectious disease of humans, particularly children,…
- Smegma ‐ A foul-smelling accumulation of SEBUM and desquaminated epidermal…
- Filtration Implants, Glaucoma ‐ Devices, usually incorporating unidirectional valves, which are…
- Diseases, Sclera ‐ General disorders of the sclera or white of the eye. They may…
- Dehydrogenase, NADPH-Dependent Glutamate ‐ An enzyme that catalyzes the conversion of L-glutamate, H2O,…
- Orofacial Dyskinesias, Idiopathic ‐ A syndrome characterized by orofacial DYSTONIA; including BLEPHAROSPASM;…
- Voluntary Male Sterilizations ‐ Procedures for the purpose of rendering individuals incapable…