About The Medical Condition Resistance-Associated Protein, Multidrug
Find the definition of the medical term Resistance-Associated Protein, Multidrug. Resistance-Associated Protein, Multidrug defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Resistance-Associated Protein, Multidrug
| Resistance-Associated Protein, Multidrug Medical Condition |
|---|
What's The Definition Of The Medical Condition Resistance-Associated Protein, Multidrug?
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the p-glycoprotein family of proteins.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Teaching, Remedial ‐ Specialized instruction for students deviating from the expected…
- Tetracemate ‐ A chelating agent (CHELATING AGENTS) that sequesters a variety…
- Ductal Carcinomas ‐ An invasive (infiltrating) carcinoma of the breast. This carcinoma…
- Record, Hospital ‐ Compilations of data on hospital activities and programs; excludes…
- Sodium Ion Channels ‐ Cell membrane glycoproteins selective for sodium ions. Fast sodium…
- Relation, Centric ‐ The location of the maxillary and the mandibular condyles when…
- Pattern, Feeding ‐ Behavioral responses or sequences associated with eating including…
- Rhamnose ‐ A methylpentose whose L- isomer is found naturally in many plant…
- Dexon-S ‐ A biocompatible polymer used as a surgical suture…
- Interferon Alfa-2c, Recombinant ‐ A recombinant alfa interferon consisting of 165 amino acids with…