About The Medical Condition Retinoblastoma Gene
Find the definition of the medical term Retinoblastoma Gene. Retinoblastoma Gene defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Retinoblastoma Gene
| Retinoblastoma Gene Medical Condition |
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What's The Definition Of The Medical Condition Retinoblastoma Gene?
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
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