About The Medical Condition SCF Receptor

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Find the definition of the medical term SCF Receptor. SCF Receptor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

SCF Receptor

SCF Receptor Medical Condition Defined & Explained
SCF Receptor Medical Condition

What's The Definition Of The Medical Condition SCF Receptor?

A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.

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