About The Medical Condition Shwartzman Phenomenon
Find the definition of the medical term Shwartzman Phenomenon. Shwartzman Phenomenon defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Shwartzman Phenomenon
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What's The Definition Of The Medical Condition Shwartzman Phenomenon?
A vasculitis, local or systemic, caused by a two-stage reaction in which a first encounter with endotoxin produces intravascular fibrin thrombi whose clearance results in reticuloendothelial blockade which prevents the clearance of thrombi caused by a second encounter with endotoxin, (or a variety of polyanions, glycogen or antigen/antibody complexes) resulting in tissue necrosis and/or hemorrhage. In pregnancy gram-negative septicemia during delivery or abortion may serve as the first or provocative encounter.
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