About The Medical Condition Simvastatin
Find the definition of the medical term Simvastatin. Simvastatin defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Simvastatin
| Simvastatin Medical Condition |
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What's The Definition Of The Medical Condition Simvastatin?
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL-cholesterol (LIPOPROTEINS, LDL CHOLESTEROL).
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