About The Medical Condition Spastic Paraplegia, Tropical

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Spastic Paraplegia, Tropical

Spastic Paraplegia, Tropical Medical Condition Defined & Explained
Spastic Paraplegia, Tropical Medical Condition

What's The Definition Of The Medical Condition Spastic Paraplegia, Tropical?

A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by human T-cell leukemia virus type I (HUMAN T-LYMPHOTROPIC VIRUS 1). Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

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