About The Medical Condition Spastic Paraplegias, Hereditary
Find the definition of the medical term Spastic Paraplegias, Hereditary. Spastic Paraplegias, Hereditary defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Spastic Paraplegias, Hereditary
| Spastic Paraplegias, Hereditary Medical Condition |
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What's The Definition Of The Medical Condition Spastic Paraplegias, Hereditary?
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progessive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
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