About The Medical Condition Spongiform Encephalopathy, Subacute
Find the definition of the medical term Spongiform Encephalopathy, Subacute. Spongiform Encephalopathy, Subacute defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Spongiform Encephalopathy, Subacute
Spongiform Encephalopathy, Subacute Medical Condition |
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What's The Definition Of The Medical Condition Spongiform Encephalopathy, Subacute?
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
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