About The Medical Condition Supranuclear Ophthalmoplegia, Progressive
Find the definition of the medical term Supranuclear Ophthalmoplegia, Progressive. Supranuclear Ophthalmoplegia, Progressive defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Supranuclear Ophthalmoplegia, Progressive
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What's The Definition Of The Medical Condition Supranuclear Ophthalmoplegia, Progressive?
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
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