About The Medical Condition Syndrome, Kallmann
Find the definition of the medical term Syndrome, Kallmann. Syndrome, Kallmann defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Syndrome, Kallmann
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What's The Definition Of The Medical Condition Syndrome, Kallmann?
Congenital and familial disorder characterized by hypogonadotropic hypogonadism, eunuchoidal features, and anosmia or hyposmia. It is caused by a defect in the synthesis and/or release of LHRH (luteinizing hormone-releasing hormone; GONADORELIN) from the hypothalamus as a result of faulty embryonic neuronal migration. The gene responsible for this is found in the region Xp22.3 on the short arm of the X chromosome. There is a homolog on the Y chromosome. The syndrome is more prevalent in males by a ratio of three to one.
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