About The Medical Condition Synthetase, 5-Aminolevulinate
Find the definition of the medical term Synthetase, 5-Aminolevulinate. Synthetase, 5-Aminolevulinate defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Synthetase, 5-Aminolevulinate
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What's The Definition Of The Medical Condition Synthetase, 5-Aminolevulinate?
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyl phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis and, in liver at least, is feedback inhibited by heme. (Dorland, 28th ed) EC 2.3.1.37.
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