About The Medical Condition Synthetase, Aminolevulinic Acid
Find the definition of the medical term Synthetase, Aminolevulinic Acid. Synthetase, Aminolevulinic Acid defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Synthetase, Aminolevulinic Acid
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What's The Definition Of The Medical Condition Synthetase, Aminolevulinic Acid?
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyl phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis and, in liver at least, is feedback inhibited by heme. (Dorland, 28th ed) EC 2.3.1.37.
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