About The Medical Condition Synthetase, Estrogen
Find the definition of the medical term Synthetase, Estrogen. Synthetase, Estrogen defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Synthetase, Estrogen
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What's The Definition Of The Medical Condition Synthetase, Estrogen?
An enzyme which converts androgens to estrogens by desaturating ring A of the steroid. This enzyme complex is located in the endoplasmic reticulum of estrogen-producing cells including ovaries, placenta, testicular Sertoli and Leydig cells, adipose, and brain tissues. The enzyme complex has two components, one of which is the CYP19 gene product, the aromatase cytochrome P-450. The other component is NADPH-cytochrome P-450 reductase which transfers reducing equivalents to P-450(arom). EC 1.14.13.-.
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