About The Medical Condition TIMP
Find the definition of the medical term TIMP. TIMP defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
TIMP
| TIMP Medical Condition |
|---|
What's The Definition Of The Medical Condition TIMP?
A family of secreted proteins (TIMP-1; TIMP-2; and TIMP-3) that play a crucial role in regulating the activity of the secreted METALLOENDOPEPTIDASES (COLLAGENASES; stromelysins, GELATINASES). Of the three characterized, only TIMP-1 and TIMP-2 appear to have related primary structures and inhibitory properties. They influence the activation of the prometalloproteinase and act to modulate proteolysis of extracellular matrix, notably during tissue remodeling and inflammatory processes. On certain cell types, they can exhibit growth factor-like activity, and they can inhibit the tumorigenic and metastatic phenotype in cancer cells. (Pharmacol Ther 1993;59:329-41)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Rhythm, Alpha ‐ One of four types of brain waves characterized by a relatively…
- Gland Diseases, Sebaceous ‐ Diseases of the sebaceous glands such as sebaceous hyperplasia…
- Monitoring, Physiologic ‐ The continuous measurement of physiological processes, blood…
- Extranuclear Inheritance ‐ Vertical transmission of hereditary characters by DNA from cytoplasmic…
- Benzol ‐ Toxic, volatile, flammable liquid hydrocarbon biproduct of coal…
- Herpesviridae Infection ‐ Virus diseases caused by the…
- ICI50172 ‐ A beta-adrenergic antagonist that has been used in the emergency…
- Sulfonate, Ethylmethane ‐ An antineoplastic agent with alkylating properties. It also acts…
- Atonic Neurogenic Bladder ‐ Dysfunction of the urinary bladder due to disease of the central…
- Restryl ‐ Histamine H1 antagonist with sedative action used as a hypnotic…