About The Medical Condition Transforming Growth Factor beta
Find the definition of the medical term Transforming Growth Factor beta. Transforming Growth Factor beta defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Transforming Growth Factor beta
| Transforming Growth Factor beta Medical Condition |
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What's The Definition Of The Medical Condition Transforming Growth Factor beta?
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
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