About The Medical Condition Translocation, Bacterial
Find the definition of the medical term Translocation, Bacterial. Translocation, Bacterial defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Translocation, Bacterial
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What's The Definition Of The Medical Condition Translocation, Bacterial?
The passage of viable bacteria from the gastrointestinal tract to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the intestinal mucosa resulting in increased intestinal permeability. These mechanisms can act in concert to promote synergistically the systemic spread of indigenous translocating bacteria to cause lethal sepsis.
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