About The Medical Condition Tumors, Endodermal Sinus
Find the definition of the medical term Tumors, Endodermal Sinus. Tumors, Endodermal Sinus defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Tumors, Endodermal Sinus
| Tumors, Endodermal Sinus Medical Condition |
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What's The Definition Of The Medical Condition Tumors, Endodermal Sinus?
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
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