About The Medical Condition Type III Hereditary Sensory Neuropathy, Dominant

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Find the definition of the medical term Type III Hereditary Sensory Neuropathy, Dominant. Type III Hereditary Sensory Neuropathy, Dominant defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Type III Hereditary Sensory Neuropathy, Dominant

Type III Hereditary Sensory Neuropathy, Dominant Medical Condition Defined & Explained
Type III Hereditary Sensory Neuropathy, Dominant Medical Condition

What's The Definition Of The Medical Condition Type III Hereditary Sensory Neuropathy, Dominant?

An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

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