About The Medical Condition Variable Region

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Find the definition of the medical term Variable Region. Variable Region defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Variable Region

Variable Region Medical Condition Defined & Explained
Variable Region Medical Condition

What's The Definition Of The Medical Condition Variable Region?

That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

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