About The Medical Condition VIIIa, Coagulation Factor

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Find the definition of the medical term VIIIa, Coagulation Factor. VIIIa, Coagulation Factor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

VIIIa, Coagulation Factor

VIIIa, Coagulation Factor Medical Condition Defined & Explained
VIIIa, Coagulation Factor Medical Condition

What's The Definition Of The Medical Condition VIIIa, Coagulation Factor?

Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.

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