About The Medical Condition Zinc Finger Motif
Find the definition of the medical term Zinc Finger Motif. Zinc Finger Motif defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Zinc Finger Motif
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What's The Definition Of The Medical Condition Zinc Finger Motif?
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
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