About The Word 2,3-Bisphosphate, Glycerate

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Find the definition of the medical term 2,3-Bisphosphate, Glycerate. 2,3-Bisphosphate, Glycerate defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

2,3-Bisphosphate, Glycerate

2,3-Bisphosphate, Glycerate Definition & Meaning
2,3-Bisphosphate, Glycerate Definition And Meaning

What's The Definition Of Medical Term 2,3-Bisphosphate, Glycerate?

A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)

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