About The Word 2-Microglobulin, beta
Find the definition of the medical term 2-Microglobulin, beta. 2-Microglobulin, beta defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.
2-Microglobulin, beta
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What's The Definition Of Medical Term 2-Microglobulin, beta?
An 11 kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
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