About The Word 2-Microglobulin, beta

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Find the definition of the medical term 2-Microglobulin, beta. 2-Microglobulin, beta defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

2-Microglobulin, beta

2-Microglobulin, beta Definition & Meaning
2-Microglobulin, beta Definition And Meaning

What's The Definition Of Medical Term 2-Microglobulin, beta?

An 11 kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.

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