About The Word BRCA2 Genes

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Find the definition of the medical term BRCA2 Genes. BRCA2 Genes defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

BRCA2 Genes

BRCA2 Genes Definition & Meaning
BRCA2 Genes Definition And Meaning

What's The Definition Of Medical Term BRCA2 Genes?

A tumor suppressor gene (GENES, SUPPRESSOR, TUMOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)

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