About The Word BRCA2 Genes
Find the definition of the medical term BRCA2 Genes. BRCA2 Genes defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.
BRCA2 Genes
BRCA2 Genes Definition And Meaning |
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What's The Definition Of Medical Term BRCA2 Genes?
A tumor suppressor gene (GENES, SUPPRESSOR, TUMOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)
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