About The Word Fibroblast Growth Factor, Basic
Find the definition of the medical term Fibroblast Growth Factor, Basic. Fibroblast Growth Factor, Basic defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.
Fibroblast Growth Factor, Basic
| Fibroblast Growth Factor, Basic Definition And Meaning |
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What's The Definition Of Medical Term Fibroblast Growth Factor, Basic?
A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
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