About The Word Myb Gene

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Find the definition of the medical term Myb Gene. Myb Gene defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

Myb Gene

Myb Gene Definition & Meaning
Myb Gene Definition And Meaning

What's The Definition Of Medical Term Myb Gene?

Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).

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