About The Word Rb Genes

ClusterMed

Find the definition of the medical term Rb Genes. Rb Genes defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

Rb Genes

Rb Genes Definition & Meaning
Rb Genes Definition And Meaning

What's The Definition Of Medical Term Rb Genes?

Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

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