About The Medical Condition Monacolin K
Find the definition of the medical term Monacolin K. Monacolin K defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Monacolin K
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What's The Definition Of The Medical Condition Monacolin K?
A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
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