About The Medical Condition Monosodium Salt, Cilastatin
Find the definition of the medical term Monosodium Salt, Cilastatin. Monosodium Salt, Cilastatin defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Monosodium Salt, Cilastatin
| Monosodium Salt, Cilastatin Medical Condition |
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What's The Definition Of The Medical Condition Monosodium Salt, Cilastatin?
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukeotriene E4.
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