About The Medical Condition Motif, HTH
Find the definition of the medical term Motif, HTH. Motif, HTH defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Motif, HTH
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What's The Definition Of The Medical Condition Motif, HTH?
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
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