About The Medical Condition Motifs, E-Box

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Find the definition of the medical term Motifs, E-Box. Motifs, E-Box defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Motifs, E-Box

Motifs, E-Box Medical Condition Defined & Explained
Motifs, E-Box Medical Condition

What's The Definition Of The Medical Condition Motifs, E-Box?

DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS (GENETICS) may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.

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