About The Medical Condition Mouse, Inbred mdx
Find the definition of the medical term Mouse, Inbred mdx. Mouse, Inbred mdx defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Mouse, Inbred mdx
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What's The Definition Of The Medical Condition Mouse, Inbred mdx?
A strain of mice arising from a spontaneous mutation (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein dystrophin, have high serum levels of muscle enzymes, and possess histological lesions similar to human muscular dystrophy. The histological features, linkage, and map position of mdx make these mice a worthy animal model of Duchenne muscular dystrophy.
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