About The Medical Condition Mouse, MRL lpr
Find the definition of the medical term Mouse, MRL lpr. Mouse, MRL lpr defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Mouse, MRL lpr
| Mouse, MRL lpr Medical Condition |
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What's The Definition Of The Medical Condition Mouse, MRL lpr?
A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
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