About The Medical Condition NMDA Receptor-Ionophore Complex
Find the definition of the medical term NMDA Receptor-Ionophore Complex. NMDA Receptor-Ionophore Complex defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
NMDA Receptor-Ionophore Complex
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What's The Definition Of The Medical Condition NMDA Receptor-Ionophore Complex?
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
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