About The Medical Condition Nucleotide Excision Repair
Find the definition of the medical term Nucleotide Excision Repair. Nucleotide Excision Repair defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Nucleotide Excision Repair
| Nucleotide Excision Repair Medical Condition |
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What's The Definition Of The Medical Condition Nucleotide Excision Repair?
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
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