About The Medical Condition Thapsigargin
Find the definition of the medical term Thapsigargin. Thapsigargin defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Thapsigargin
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What's The Definition Of The Medical Condition Thapsigargin?
A potent skin irritating sesquiterpene lactone isolated from the roots of Thapsia garganica L. (Apiaceae). It also acts as a non-phorbol-ester-type tumor promoter which discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca(2+)-ATPase. (Biochem Pharmacol 1987;36(5):621-6; Proc Natl Acad Sci USA 1991;88(16):7096-100)
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