About The Word Region, Complementarity Determining

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Find the definition of the medical term Region, Complementarity Determining. Region, Complementarity Determining defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

Region, Complementarity Determining

Region, Complementarity Determining Definition & Meaning
Region, Complementarity Determining Definition And Meaning

What's The Definition Of Medical Term Region, Complementarity Determining?

Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).

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