About The Word Spastic Paraplegia, Autosomal Dominant, Hereditary

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Find the definition of the medical term Spastic Paraplegia, Autosomal Dominant, Hereditary. Spastic Paraplegia, Autosomal Dominant, Hereditary defined and explained for easy understanding at the Medical Dictionary from ClusterMed.info.

Spastic Paraplegia, Autosomal Dominant, Hereditary

Spastic Paraplegia, Autosomal Dominant, Hereditary Definition & Meaning
Spastic Paraplegia, Autosomal Dominant, Hereditary Definition And Meaning

What's The Definition Of Medical Term Spastic Paraplegia, Autosomal Dominant, Hereditary?

A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progessive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)

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