About The Medical Condition Akinetic-Rigid Variant of Huntington Disease

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Find the definition of the medical term Akinetic-Rigid Variant of Huntington Disease. Akinetic-Rigid Variant of Huntington Disease defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Akinetic-Rigid Variant of Huntington Disease

Akinetic-Rigid Variant of Huntington Disease Medical Condition Defined & Explained
Akinetic-Rigid Variant of Huntington Disease Medical Condition

What's The Definition Of The Medical Condition Akinetic-Rigid Variant of Huntington Disease?

A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse CHOREA involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

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