About The Medical Condition Helix-Turn-Helix Motif
Find the definition of the medical term Helix-Turn-Helix Motif. Helix-Turn-Helix Motif defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Helix-Turn-Helix Motif
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What's The Definition Of The Medical Condition Helix-Turn-Helix Motif?
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
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