About The Medical Condition HER-2 Proto-Oncogene Protein
Find the definition of the medical term HER-2 Proto-Oncogene Protein. HER-2 Proto-Oncogene Protein defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
HER-2 Proto-Oncogene Protein
| HER-2 Proto-Oncogene Protein Medical Condition |
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What's The Definition Of The Medical Condition HER-2 Proto-Oncogene Protein?
A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. EC 2.7.11.-.
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