About The Medical Condition Heterozygosity, Loss of
Find the definition of the medical term Heterozygosity, Loss of. Heterozygosity, Loss of defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Heterozygosity, Loss of
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What's The Definition Of The Medical Condition Heterozygosity, Loss of?
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair. It is detected when heterozygous markers for a locus appear monomorphic because one of the alleles was deleted. When this occurs at a tumor suppressor gene locus where one of the alleles is already abnormal, it can result in neoplastic transformation.
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