About The Medical Condition HLA-B

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Find the definition of the medical term HLA-B. HLA-B defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

HLA-B

HLA-B Medical Condition Defined & Explained
HLA-B Medical Condition

What's The Definition Of The Medical Condition HLA-B?

Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

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