About The Medical Condition HLA-C Antigens

Find the definition of the medical term HLA-C Antigens. HLA-C Antigens defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
HLA-C Antigens

HLA-C Antigens Medical Condition |
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What's The Definition Of The Medical Condition HLA-C Antigens?
Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
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