About The Medical Condition Holmes-Adie Syndrome

Find the definition of the medical term Holmes-Adie Syndrome. Holmes-Adie Syndrome defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Holmes-Adie Syndrome

Holmes-Adie Syndrome Medical Condition |
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What's The Definition Of The Medical Condition Holmes-Adie Syndrome?
A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
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