Learn about the disease, illness and/or condition MELAS Syndrome including: symptoms, causes, treatments, contraindications and conditions at ClusterMed.info.
MELAS Syndrome Information
Are there other mitochondrial diseases?
Yes, mutations (genetic changes) in the mitochondrial chromosome are responsible for a number of other disorders aside from MELAS such as:
How is MELAS diagnosed?
The diagnosis of MELAS is usually suspected on clinical grounds. However, confirmation of the diagnosis usually requires a muscle or brain biopsy. The muscle biopsy shows characteristic ragged red fibers; a brain biopsy shows stroke-like changes.
How is MELAS treated?
There is no known treatment for the underlying disease, which is progressive and fatal. Patients are managed according to what areas of the body are affected at a particular time. antioxidants and vitamins have been used, but there have been no consistent successes reported.
What are the symptoms of MELAS?
As a result of the disturbed function of their cells' mitochondria, patients with MELAS develop
What causes MELAS?
MELAS syndrome is caused by mutations in the genetic material (DNA) in the mitochondria. While most of our DNA is in the chromosomes in the cell nucleus, some of our DNA is in another important structure called the mitochondrion (plural: mitochondria). The mitochondria are located outside the nucleus in the cell's cytoplasm. Each mitochondrion has a chromosome made of DNA that is quite different from the better known chromosomes in the nucleus. The mitochondrial chromosome is much smaller; it is round (whereas the chromosomes in the nucleus are normally shaped like rods); there are many copies of the mitochondrial chromosome in every cell; and no matter whether we are male or female, we inherit all of our mitochondrial chromosome from our mother. Much of the DNA in our mitochondria is used to manufacture proteins involved in the key function of mitochondria -- to produce energy and power the cells in our body.
What is MELAS?
MELAS is a rare genetic disorder which results in stroke and dementia. MELAS is an abbreviation that stands for Mitochondrial Encephalopathy, Lactic acidosis, and Stroke-like episodes.
When do people with MELAS develop symptoms?
MELAS can affect people at very different times in life, ranging from age 4 to age 40 or more. However, most patients with MELAS syndrome show symptoms before they are 20 years old.
Diseases & Illnesses Definitions Of The Day
- Miliaria (Heat Rash) ‐
- Adult Behavior Disorders (Mental Health (Psychology)) ‐ Can mental health disorders be prevented?, How is mental illness diagnosed? …
- Toxic Shock Syndrome (TSS) ‐ How do physicians diagnose toxic shock syndrome?, Is it possible to prevent toxic shock syndrome? …
- Arthritis, Scleroderma (Scleroderma) ‐ How do health care professionals make a diagnosis of scleroderma? …
- Nosebleed ‐ How do you prevent the nose from bleeding again?, How do you stop the common nosebleed? …
- High Altitude Pulmonary Edema (Pulmonary Edema) ‐ How can pulmonary edema be prevented?, How is the condition diagnosed? …
- Basal Body Temperature Methods to Conceive (Trying to Conceive) ‐ Counseling and support groups for help, Taking your temperature to conceive …
- Diverticulitis (Diverticulosis) ‐
- Kernicterus ‐ How is newborn jaundice diagnosed?, Newborn jaundice and kernicterus facts …
- Thyroid Blood Tests ‐ Are there other tests of the thyroid gland?, How is hypothyroidism diagnosed? …