Diseases

To do an IVC, an iodine-containing dye is injected intravenously into the blood. The dye is then removed from blood by the liver which excretes it into the bile. The iodine is concentrated enough just as it is secreted into bile that it does not need to be further concentrated by the gallbladder in order to outline the bile ducts and any gallstones that may be within them. The gallbladder is not always seen on an IVC since the iodine-containing bile may bypass the gallbladder entirely and empty directly into the small intestine.

Occasional serious allergic reactions can occur to any iodine-containing dye. These reactions can usually be treated but they rarely may result in the death of the patient.

The intravenous cholangiogram or IVC is a radiologic (x-ray) procedure that is used primarily to look at the larger bile ducts within the liver and the bile ducts outside the liver. The procedure can be used to locate gallstones within these bile ducts. IVC also can be used to identify other causes of obstruction to the flow of bile, for example, narrowings (strictures) of the bile ducts and cancers that may impair the normal flow of bile.

The IVC is not used nearly as much today as it used to be. Its use always was limited because it did not work when there was more than a minimal amount of jaundice, and many of the conditions it was used for caused substantial jaundice. The IVC has been largely replaced by other diagnostic procedures -- by ERCP (endoscopic retrograde cholangiopancreatography), endoscopic ultrasound and, increasingly, by MRI cholangiography, none of which are affected by jaundice.